Cyclen
CAS NO：294-90-6
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Product Usage
Specification
Cyclen, an analog of aza-crown ethers, serves as a precursor for the preparation of magnetic resonance imaging (MRI) contrast agents. It is also an intermediate for the synthesis of effective macrocyclic chelates, such as those used in the synthesis of contrast agents for brain and spinal cord MRI imaging. These contrast agents enable accurate determination of the precise location of tumors and other lesions.
Cyclen is an important precursor for synthesizing other complex molecules, especially in pharmaceutical synthesis and materials science. For example, it can be used to prepare DOTA derivatives, which have applications in radiolabeling and targeted therapy with promising prospects.
In supramolecular chemistry, Cyclen, as a macrocyclic tetraamine, can form stable complexes with metal ions, which are used for studying molecular recognition and supramolecular chemistry.
Cyclen is used as a catalyst in the Henry reaction (nitroalkane reaction). This reaction, which is used in organic synthesis, is useful for forming carbon-carbon bonds and is particularly valuable for the synthesis of complex organic molecules.
Molecular mass
172.27
Molecular formula
C8H20N4
Appearance
White or slightly yellow crystalline powder
Water content
≤1.0%
Residue on ignition
≤0.5%
Elemental impurities
≤20ppm
Toluene soluble residue
≤890ppm
Acid-base titration
98.0~102.0%
Product Usage
Cyclen is an analogue of nitrogenous crown ether, serving as a precursor for the preparation of magnetic resonance imaging (MRI) contrast agents. It also serves as an intermediate for the synthesis of effective macrocyclic chelating agents, such as gadobutrol, used in MRI imaging of the brain and spinal cord to accurately determine the precise location of lesions such as tumors.
Cyclen is an important precursor for synthesizing other complex molecules, especially in pharmaceutical synthesis and materials science. For example, it can be used to prepare DOTA derivatives, which have applications in radiolabeling and targeted therapy with promising prospects.
In supramolecular chemistry, Cyclen, as a macrocyclic tetraamine, can form stable complexes with metal ions, which are used for studying molecular recognition and supramolecular chemistry.
Cyclen is used as a catalyst in the Henry reaction (nitroalkane reaction). This reaction, which is used in organic synthesis, is useful for forming carbon-carbon bonds and is particularly valuable for the synthesis of complex organic molecules.
Specification
Molecular mass
172.27
Molecular formula
C8H20N4
Appearance
White or slightly yellow crystalline powder
Water content
≤1.0%
Residue on ignition
≤0.5%
Elemental impurities
≤20ppm
Toluene soluble residue
≤890ppm
Acid-base titration
98.0~102.0%
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Manager Wang：(+86)18321962163
Manager Zhang：(+86)19822737233
Email: sales@eyougene.com
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Shanghai Eyougene Biotechnology Development CO.,LTD.
Contact us
Manager Wang：(+86)18321962163
Manager Zhang：(+86)19822737233
Email: sales@eyougene.com
Scan the QR code and follow us
Follow our WeChat official account
Shanghai Eyougene Biotechnology Development CO.,LTD.
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About Eyougene
Shanghai Eyougene Co., Ltd. is a next-generation digital enterprise based on its own leading chemical technology, focusing on the fields of pharmaceuticals and new materials. We are committed to providing one-stop solutions for customers in the fields of innovative drugs and new materials both domestically and internationally.
Since its establishment in 2015, Eyougene has experienced rapid development, steadily achieving integration from market, research and development to manufacturing facilities, possessing integrated operational capabilities from research and development to commercialization. The company currently has three research centers located in core cities such as Shanghai, Xi'an, and Wuhan, equipped with advanced reaction equipment and detection instruments including Lauda temperature control, fixed bed reactors, pressure reactors, HPLC-MS, and more. Our GMP & FDA dual-certified factory is located in the picturesque and conveniently located Jiande, Hangzhou, built entirely according to GMP standards and utilizing DCS automated control management. It is capable of conducting various special reactions and high-standard experiments. This GMP factory has passed audits from several top global companies, and its system capabilities have been widely recognized.
Eyougene's founding team and core members come from top universities and research institutes both domestically and abroad. With years of accumulation, we have incubated several distinctive technology platforms and developed a rich product pipeline. Our company has earned high-quality business from domestic and international leading enterprises and received wide acclaim from customers due to our high-level product quality and competitive cost advantages.
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